产品货号：
Z35852
中文名称：
PDCD4抗体
英文名称：
Anti-PDCD4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PDCD4 Antibody |
| 指标别名 | H731;Nuclear antigen H731 like;PDCD4;Protein 197/15a |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PDCD4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human PDCD4 PDCD4 (programmed cell death protein 4) was identified as a suppressor of neoplastic transformation.It interacts with eukaryotic initiation factors eIF4AI and eIF4AII.PDCD4 colocalizes with eIF4A in the cytoplasm and inhibits the activity of eIF4A as an ATP-dependent RNA helicase. |
| 实际分子量 | 52～60KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Programmed cell death protein 4 (PDCD4) is a protein that in humans is encoded by the PDCD4 gene.It is mapped to 10q25.2.This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding.It also encodes a protein localized to the nucleus in proliferating cells.Expression of this gene is modulated by cytokines in natural killer and T cells.The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. |
| Uniprot ID | Q53EL6 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Flow cytometry (FCM) 1:20 |
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